We further dissected phenotypic correlations into genetic and environmental components by performing quantitative genetic variance decomposition analyses in the whole Caucasian sample 4, subjects using the program SOLAR available on http: J Bone Miner Res Reid IR, Plank LD et al Fat mass is an important determinant of whole body bone density in premenopausal women but not in men.
Regul Pept Research design and methods Subjects The study population consisted of two samples. Curr Osteoporos Rep. Several environmental, nutritional, and hormonal factors appear to influence body obesitas osteoporosis. Osteoporosis is a skeletal disease characterized by a reduction in bone mass; it is typically defined in an individual with a bone mineral density BMD T-score that is 2.
The Caucasian sample has a higher average age than the Chinese sample. We adopted an exclusion criterion elaborated elsewhere Arden N. Int J Prev Med. Accessed 27 Jan Dia mengatakan: Effect of fat on measurement of bone mineral density.
Looking beyond bone mineral density: Further, increasing evidence seems to indicate that different components of the metabolic syndrome, ie, hypertension, increased triglycerides, reduced high-density lipoprotein cholesterol, are also potential risk factors for the development of low bone mineral density and osteoporosis.
Associations of fat mass and fat distribution with bone mineral density in pre- and postmenopausal Chinese women. Childhood obesity is associated with increased risk of most lower extremity fractures. One potential problem with these phenoytpic studies is that the correlation between body weight or BMI and bone mass may not necessarily represent a correlation between obesity per se and osteoporosis, as it is excessive fat mass, rather than total body weight, that defines obesity.
In contrast to these findings, however, systemic administration of leptin to leptin-deficient mice, and wild-type mice results in increased bone growth, increased skeletal mass, and increased skeletal strength 6. Based on these observations, it was proposed that leptin may inhibit bone formation 8.robadarocker.com - Obesitas telah menjadi epidemi berbahaya yang mampu memicu berbagai macam penyakit kronis.
Mulai dari stroke, serangan jantung, tekanan darah tinggi, hingga yang terbaru yaitu osteoporosis. The relationship between obesity and osteoporosis has been widely studied, and epidemiological evidence shows that obesity is correlated with increased bone mass.
Previous analyses, however, did not control for the mechanical loading effects of total body weight on bone mass and may have generated a confounded or even biased relationship between obesity and robadarocker.com by: There are several risk factors that have been identified for osteoporosis.
Until recently, obesity was thought to be protective for osteoporosis and associated with decreased fragility fracture risk; however, recent evidence challenges this assumption.
This review will discuss the relationship between obesity and osteoporosis, as well as the utility of various bone imaging techniques when applied to obese Cited by: 5. Beberapa orang peneliti dari Harvard Medical School menemukan seseorang yang memiliki kelebihan berat badan (obesitas) menyimpan lemak dalam tulang mereka yang dapat menyebabkan kerapuhan serta dapat menyebabkan tulang mudah mengalami keretakan.
Peneliti dari Amerika Serikat tepatnya menemukan bahwa beberapa orang yang kelebihan berat badan ternyata memiliki lemak yang tersembunyi di tulangnya.
Abstract. The belief that obesity is protective against osteoporosis has recently been revised. In fact latest epidemiologic and clinical studies show that a high level of fat mass, but also reduced muscle mass, might be a risk factor for osteoporosis and fragility robadarocker.com by: 1.